AFC Wimbledon have played Guiseley 1 times in competitive football, winning 1, drawing 0 and losing 0, first meeting on 6 Nov 2021 and most recently on 6 Nov 2021. Every meeting is listed below.
| Date | Season | Competition | Venue | Opponent | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 6 Nov 2021 | 2021–22 | FA Cup | H | Guiseley | 1–0 | Ollie Palmer 44 | 4,973 |
All AFC Wimbledon head-to-head records · AFC Wimbledon season by season