Chelsea have played S.S. Lazio 4 times in competitive football, winning 2, drawing 1 and losing 1, first meeting on 7 Dec 1999 and most recently on 4 Nov 2003. Every meeting is listed below.
| Date | Season | Competition | Venue | Opponent | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 7 Dec 1999 | 1999–00 | Champions League | A | S.S. Lazio | 0–0 | 38,662 | |
| 22 Mar 2000 | 1999–00 | Champions League | H | S.S. Lazio | 1–2 | Gustavo Poyet 44 | 34,260 |
| 22 Oct 2003 | 2003–04 | Champions League | H | S.S. Lazio | 2–1 | Frank Lampard 57, Adrian Mutu 65 | 40,405 |
| 4 Nov 2003 | 2003–04 | Champions League | A | S.S. Lazio | 4–0 | Hernan Crespo 15, Eiður Guðjohnsen 70, Damien Duff 75, Frank Lampard 80 | 50,000 |