Sheffield Wednesday have played Southport 1 times in competitive football, winning 1, drawing 0 and losing 0, first meeting on 7 Nov 2010 and most recently on 7 Nov 2010. Every meeting is listed below.
| Date | Season | Competition | Venue | Opponent | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 7 Nov 2010 | 2010–11 | FA Cup | A | Southport | 5–2 |
All Sheffield Wednesday head-to-head records · Sheffield Wednesday season by season