Every competitive match Southampton played in 1905–06, in Southern League — 5 matches, 3 won, 1 drawn, 1 lost, with scorers and attendances where the record holds them.
| Date | Competition | Venue | Opponent | Their season | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 13 Jan 1906 | FA Cup | H | Portsmouth | Portsmouth 1905–06 | 5–1 | ||
| 3 Feb 1906 | FA Cup | A | New Brompton | 0–0 | |||
| 7 Feb 1906 | FA Cup | H | New Brompton | 1–0 | |||
| 24 Feb 1906 | FA Cup | H | Middlesbrough | Middlesbrough 1905–06 | 6–1 | ||
| 10 Mar 1906 | FA Cup | A | Liverpool | Liverpool 1905–06 | 0–3 |
All 123 Southampton seasons · Southampton head-to-head records · Southampton players