Every competitive match Leyton Orient played in 1945–46, in Third Division South — 2 matches, 1 won, 0 drawn, 1 lost, with scorers and attendances where the record holds them.
| Date | Competition | Venue | Opponent | Their season | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 17 Nov 1945 | FA Cup | H | Newport IOW | 2–1 | |||
| 24 Nov 1945 | FA Cup | A | Newport IOW | 0–2 |
All 111 Leyton Orient seasons · Leyton Orient head-to-head records · Leyton Orient players