Every competitive match Arsenal played in 2000–01 — 59 matches, 32 won, 13 drawn, 14 lost, with scorers and attendances where the record holds them.
| Date | Competition | Venue | Opponent | Their season | Score | Scorers | Att |
|---|---|---|---|---|---|---|---|
| 19 Aug 2000 | Premier League | A | Sunderland | Sunderland 2000–01 | 0–1 | 46,347 | |
| 21 Aug 2000 | Premier League | H | Liverpool | Liverpool 2000–01 | 2–0 | Lauren 8, Thierry Henry 89 | 38,014 |
| 26 Aug 2000 | Premier League | H | Charlton Athletic | Charlton Athletic 2000–01 | 5–3 | Patrick Vieira 19, Thierry Henry 46, Patrick Vieira 61, Thierry Henry 67, Sylvinho 89 | 38,025 |
| 6 Sep 2000 | Premier League | A | Chelsea | Chelsea 2000–01 | 2–2 | Thierry Henry 76, Sylvinho 86 | 34,923 |
| 9 Sep 2000 | Premier League | A | Bradford City | Bradford City 2000–01 | 1–1 | Ashley Cole 66 | 17,160 |
| 12 Sep 2000 | Champions League | A | AC Sparta Prague | 1–0 | Sylvinho 33 | 17,666 | |
| 16 Sep 2000 | Premier League | H | Coventry City | Coventry City 2000–01 | 2–1 | Sylvain Wiltord 24, Paolo Vernazza 72 | 37,794 |
| 20 Sep 2000 | Champions League | H | Shakhtar Donetsk | 3–2 | Sylvain Wiltord 45, Martin Keown 85, Martin Keown 90 | 33,922 | |
| 23 Sep 2000 | Premier League | A | Ipswich Town | Ipswich Town 2000–01 | 1–1 | Dennis Bergkamp 84 | 22,030 |
| 27 Sep 2000 | Champions League | H | S.S. Lazio | 2–0 | Freddie Ljungberg 43, Freddie Ljungberg 56 | 34,521 | |
| 1 Oct 2000 | Premier League | H | Manchester United | Manchester United 2000–01 | 1–0 | Thierry Henry 30 | 38,146 |
| 14 Oct 2000 | Premier League | H | Aston Villa | Aston Villa 2000–01 | 1–0 | Thierry Henry 61 | 38,042 |
| 17 Oct 2000 | Champions League | A | S.S. Lazio | 1–1 | Robert Pires 88 | 40,151 | |
| 21 Oct 2000 | Premier League | A | West Ham United | West Ham United 2000–01 | 2–1 | Robert Pires 12, Rio Ferdinand 21 | 26,034 |
| 25 Oct 2000 | Champions League | H | AC Sparta Prague | 4–2 | Ray Parlour 5, Lauren 8, Lee Dixon 35, Nwankwo Kanu 51 | 34,397 | |
| 28 Oct 2000 | Premier League | H | Manchester City | Manchester City 2000–01 | 5–0 | Ashley Cole 44, Dennis Bergkamp 52, Sylvain Wiltord 75, Thierry Henry 82, Thierry Henry 88 | 38,049 |
| 1 Nov 2000 | League Cup | H | Ipswich Town | Ipswich Town 2000–01 | 1–2 | Igors Stepanovs 44 | 26,105 |
| 4 Nov 2000 | Premier League | A | Middlesbrough | Middlesbrough 2000–01 | 1–0 | Thierry Henry 25 | 29,541 |
| 7 Nov 2000 | Champions League | A | Shakhtar Donetsk | 0–3 | 30,000 | ||
| 11 Nov 2000 | Premier League | H | Derby County | Derby County 2000–01 | 0–0 | 37,679 | |
| 18 Nov 2000 | Premier League | A | Everton | Everton 2000–01 | 0–2 | 33,106 | |
| 22 Nov 2000 | Champions League | A | Spartak Moscow | 1–4 | Sylvinho 2 | 63,000 | |
| 26 Nov 2000 | Premier League | A | Leeds United | Leeds United 2000–01 | 0–1 | 38,084 | |
| 2 Dec 2000 | Premier League | H | Southampton | Southampton 2000–01 | 1–0 | Claus Lundekvam 85 | 38,036 |
| 5 Dec 2000 | Champions League | H | Bayern Munich | 2–2 | Thierry Henry 4, Nwankwo Kanu 55 | 35,318 | |
| 9 Dec 2000 | Premier League | H | Newcastle United | Newcastle United 2000–01 | 5–0 | Thierry Henry 13, Ray Parlour 16, Nwankwo Kanu 52, Ray Parlour 86, Ray Parlour 90+3 | 38,052 |
| 18 Dec 2000 | Premier League | A | Tottenham Hotspur | Tottenham Hotspur 2000–01 | 1–1 | Patrick Vieira 89 | 36,062 |
| 23 Dec 2000 | Premier League | A | Liverpool | Liverpool 2000–01 | 0–4 | 44,144 | |
| 26 Dec 2000 | Premier League | H | Leicester City | Leicester City 2000–01 | 6–1 | Thierry Henry 35, Patrick Vieira 50, Thierry Henry 66, Freddie Ljungberg 75, Thierry Henry 82, Tony Adams 90 | 38,007 |
| 30 Dec 2000 | Premier League | H | Sunderland | Sunderland 2000–01 | 2–2 | Patrick Vieira 5, Lee Dixon 40 | 38,026 |
| 1 Jan 2001 | Premier League | A | Charlton Athletic | Charlton Athletic 2000–01 | 0–1 | 20,043 | |
| 6 Jan 2001 | FA Cup | A | Carlisle United | Carlisle United 2000–01 | 1–0 | Sylvain Wiltord 22 | 15,300 |
| 13 Jan 2001 | Premier League | H | Chelsea | Chelsea 2000–01 | 1–1 | Robert Pires 3 | 38,071 |
| 20 Jan 2001 | Premier League | A | Leicester City | Leicester City 2000–01 | 0–0 | 21,872 | |
| 27 Jan 2001 | FA Cup | A | Queens Park Rangers | Queens Park Rangers 2000–01 | 6–0 | Chris Plummer 32, Sylvain Wiltord 33, Matthew Rose 49, Sylvain Wiltord 56, Robert Pires 58, Dennis Bergkamp 74 | 19,003 |
| 30 Jan 2001 | Premier League | H | Bradford City | Bradford City 2000–01 | 2–0 | Ray Parlour 17, Lauren 26 | 37,318 |
| 3 Feb 2001 | Premier League | A | Coventry City | Coventry City 2000–01 | 1–0 | Dennis Bergkamp 78 | 22,035 |
| 10 Feb 2001 | Premier League | H | Ipswich Town | Ipswich Town 2000–01 | 1–0 | Thierry Henry 67 | 38,011 |
| 13 Feb 2001 | Champions League | A | Olympique Lyonnais | 1–0 | Thierry Henry 59 | 42,000 | |
| 18 Feb 2001 | FA Cup | H | Chelsea | Chelsea 2000–01 | 3–1 | Thierry Henry 52, Sylvain Wiltord 74, Sylvain Wiltord 85 | 38,096 |
| 21 Feb 2001 | Champions League | H | Olympique Lyonnais | 1–1 | Dennis Bergkamp 33 | 34,303 | |
| 25 Feb 2001 | Premier League | A | Manchester United | Manchester United 2000–01 | 1–6 | Thierry Henry 16 | 67,535 |
| 3 Mar 2001 | Premier League | H | West Ham United | West Ham United 2000–01 | 3–0 | Sylvain Wiltord 6, Sylvain Wiltord 13, Sylvain Wiltord 39 | 38,071 |
| 6 Mar 2001 | Champions League | H | Spartak Moscow | 1–0 | Thierry Henry 82 | 35,296 | |
| 10 Mar 2001 | FA Cup | H | Blackburn Rovers | Blackburn Rovers 2000–01 | 3–0 | Sylvain Wiltord 2, Tony Adams 5, Robert Pires 36 | 36,304 |
| 14 Mar 2001 | Champions League | A | Bayern Munich | 0–1 | 58,000 | ||
| 18 Mar 2001 | Premier League | A | Aston Villa | Aston Villa 2000–01 | 0–0 | 36,111 | |
| 31 Mar 2001 | Premier League | H | Tottenham Hotspur | Tottenham Hotspur 2000–01 | 2–0 | Robert Pires 70, Thierry Henry 87 | 38,121 |
| 4 Apr 2001 | Champions League | H | Valencia CF | 2–1 | Thierry Henry 58, Ray Parlour 60 | 35,104 | |
| 8 Apr 2001 | FA Cup | N | Tottenham Hotspur | Tottenham Hotspur 2000–01 | 2–1 | Patrick Vieira 33, Robert Pires 74 | 63,541 |
| 11 Apr 2001 | Premier League | A | Manchester City | Manchester City 2000–01 | 4–0 | Freddie Ljungberg 8, Sylvain Wiltord 8, Freddie Ljungberg 16, Nwankwo Kanu 36 | 33,444 |
| 14 Apr 2001 | Premier League | H | Middlesbrough | Middlesbrough 2000–01 | 0–3 | 37,879 | |
| 17 Apr 2001 | Champions League | A | Valencia CF | 0–1 | 48,000 | ||
| 21 Apr 2001 | Premier League | H | Everton | Everton 2000–01 | 4–1 | Freddie Ljungberg 21, Gilles Grimandi 55, Sylvain Wiltord 67, Thierry Henry 87 | 38,029 |
| 28 Apr 2001 | Premier League | A | Derby County | Derby County 2000–01 | 2–1 | Nwankwo Kanu 21, Robert Pires 80 | 29,567 |
| 5 May 2001 | Premier League | H | Leeds United | Leeds United 2000–01 | 2–1 | Freddie Ljungberg 17, Sylvain Wiltord 56 | 38,142 |
| 12 May 2001 | FA Cup | N | Liverpool | Liverpool 2000–01 | 1–2 | Freddie Ljungberg 72 | 72,500 |
| 15 May 2001 | Premier League | A | Newcastle United | Newcastle United 2000–01 | 0–0 | 50,729 | |
| 19 May 2001 | Premier League | A | Southampton | Southampton 2000–01 | 2–3 | Ashley Cole 28, Freddie Ljungberg 54 | 15,252 |
99 of the goals in this season carry a named scorer.
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